Year Founded: 1994
Number of Employees: Approximately 200
Contact: Tom Salus, Director of Sales
Metrics Contract Services is a leading full-service pharmaceutical
development and manufacturing organization serving clients
worldwide. We deliver proven scientific and operational
excellence for oral dosage forms. Today, as a subsidiary of Mayne
Pharma Group, we offer clients more resources and capabilities
than ever before.
Started as an analytical laboratory in 1994, Metrics has evolved into
Concept to Commercialization:
a full-service provider of:
• Quality pharmaceutical formulation development
• First-time-in-man (FTIM) formulations
• Clinical material manufacturing (CTM) for Phase I, II and III trials
• Commercial manufacturing
• Analytical testing services
• Specialty technologies for controlled release and bioavailability
The parent company of Metrics Contract Services, Mayne
Pharma, is investing $80 million to significantly expand facilities
and equipment at its site in Greenville, NC. The strategic capital
investment will fund a new 126,000-sq-ft, oral-dose commercial
manufacturing facility, quadrupling the company’s US
manufacturing capacity, while re-purposing space to create 10+
new analytical laboratories and formulation development suites.
The new facility means Metrics Contract Services can offer
a more complete “concept to commercialization” solution in
one contiguous location for clients, providing larger scale and
increased capabilities for seamless scale-up, eliminating the need
for site transfers.
Formulation development. We offer expertise in poorly soluble
and unstable actives, highly potent API, immediate and modified
release, and small molecule oral delivery.
Potent and cytotoxic products. Our cGMP compliant, dedicated
and segregated facility features custom-engineered containment.
With no open processes and one-way material flow, containment
is achieved at 30 nanograms/m3.
Fast-track development. Metrics has successfully delivered
materials for over 150 FTIM studies. Our process ensures speed
and quality, with a 16-24 week timeline from receipt of well
characterized NCE to shipment to the clinic.
Analytical testing services. With 90+ analytical chemists on
staff, our services include method development & validation,
chromatography (LC and GC), dissolution (UV and LC finish),
moisture, particle size, ion chromatography, AA/ICP, FTIR,
titrations, particulate matter (HIAC), cleaning methods (LC and
TOC), and LCMS.
Clinical trial manufacturing Phase I, II, III. Our CTM
capabilities offer capacity for up to 450Kg batch sizes. We also
offer expertise in over-encapsulation for comparator studies and
potent drug handling capabilities.
Commercial Manufacturing. Larger scale registration or
commercial manufacturing of solid oral dose formulations,
including DEA II-V controlled products.
Metrics Contract Services
1240 Sugg Parkway
Greenville, NC 27834